UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

SCHEDULE 14A INFORMATION

 

Proxy Statement Pursuant to Section 14(a) of
the Securities Exchange Act of 1934 (Amendment No. )

 

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Isis Pharmaceuticals, Inc.

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*** Exercise Your Right to Vote *** Important Notice Regarding the Availability of Proxy Materials for the Shareholder Meeting to Be Held on June 30, 2015 ISIS PHARMACEUTICALS, INC. Meeting Information Meeting Type: Annual Meeting For holders as of: May 04, 2015 Date: June 30, 2015 Time:  2:00 PM PDT Location: 2855 Gazelle Court Carlsbad, CA 92010 You are receiving this communication because you hold shares in the above named company. ISIS PHARMACEUTICALS,INC. 2855 GAZELLE COURT CARLSBAD, CA 92010 ATTN: AREF WARDAK This is not a ballot. You cannot use this notice to vote these shares. This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. You may view the proxy materials online at www.proxyvote.com or easily request a paper copy (see reverse side). We encourage you to access and review all of the important information contained in the proxy materials before voting.  See the reverse side of this notice to obtain proxy materials and voting instructions.
 
 
Before You Vote How to Access the Proxy Materials Proxy Materials Available to VIEW or RECEIVE: How to View Online: Have the information that is printed in the box marked by the arrow (located on the following page) and visit: www.proxyvote.com. How to Request and Receive a PAPER or E-MAIL Copy: If you want to receive a paper or e-mail copy of these documents, you must request one. There is NO charge for requesting a copy. Please choose one of the following methods to make your request: 1) BY INTERNET: www.proxyvote.com 2) BY TELEPHONE: 1-800-579-1639 3) BY E-MAIL*: sendmaterial@proxyvote.com * If requesting materials by e-mail, please send a blank e-mail with the information that is printed in the box marked by the arrow (located on the following page) in the subject line. 1. Form 10-K 2. Notice & Proxy Statement Requests, instructions and other inquiries sent to this e-mail address will NOT be forwarded to your investment advisor. Please make the request as instructed above on or before June 16, 2015 to facilitate timely delivery.  How To Vote Please Choose One of the Following Voting Methods Vote In Person: Many shareholder meetings have attendance requirements including, but not limited to, the possession of an attendance ticket issued by the entity holding the meeting. Please check the meeting materials for any special requirements for meeting attendance. At the meeting, you will need to request a ballot to vote these shares. Vote By Internet: To vote now by Internet, go to www.proxyvote.com. Have the information that is printed in the box marked by the arrow available and follow the instructions. Vote By Mail: You can vote by mail by requesting a paper copy of the materials, which will include a proxy card.
 
 
Voting items The Board of Directors recommends you vote FOR the following nominees to be elected for a term expiring in 2018. 1. Election of Directors Nominees 01 Breaux B. Castleman 02 Frederick T. Muto The Board of Directors recommends you vote FOR proposals 2, 3, 4 and 5. 2. Approve an amendment to the Isis Pharmaceuticals, Inc. 2011 Equity Incentive Plan to increase the aggregate number of shares of common stock authorized for issuance under the 2011 Equity Incentive Plan by 5,500,000 to an aggregate of 11,000,000 shares. 3. Approve an amendment to the Isis Pharmaceuticals, Inc. Amended and Restated 2002 Non-Employee Directors' Stock Option Plan to increase the aggregate number of shares of common stock authorized for issuance under the Amended and Restated 2002 Non-Employee Directors' Stock Option Plan by 800,000 to an aggregate of 2,000,000 shares. 4. To approve, by non-binding vote, executive compensation. 5. Ratify the Audit Committee's selection of Ernst & Young LLP as independent auditors for the 2015 fiscal year. NOTE: Such other business as may properly come before the meeting or any adjournment thereof.
 
 
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