By Joseph Walker 
 

Acquisition talks have given new momentum to Life Technologies Corp.'s (LIFE) shares after years of shareholder complaints about the company's leadership and its stock being undervalued.

For more than a decade, the Carlsbad, Calif., company operated a growing business of providing research equipment to laboratories. However, Life's share price rose slowly because of concerns about the company's management and its stumbles last year in launching its newest genetic-sequencing machines. The result prompted Life's board to say in January that it was evaluating strategic options, which reportedly include offers from lab-equipment providers attracted to the company's core business, those eyeing its newer genetics business and private-equity firms wooed by Life's balance sheet.

"Life is a company with nearly 85% recurring revenues, has the highest operating margins among its peers, and is a free-cash-flow machine," said Jonathan Groberg, an analyst at Macquarie Capital Inc. "By any objective measure, it's an attractive asset in the industry."

A buyout group--including Blackstone Group LP (BX), Carlyle Group LP (CG), KKR & Co. (KKR) and Singaporean state investment company Temasek Holdings Ltd.--is talking about a joint bid for Life of about $11 billion, or about $62 a share, said people familiar with the matter. That bid price is 66% higher than Life's 52-week low, but below the company's recent stock price of $66, which has risen 35% this year amid takeover speculation.

If the buyout group makes an offer for Life Technologies, it is likely to run up against Thermo Fisher Scientific Inc. (TMO), a maker of laboratory equipment that submitted a bid Tuesday, according to people familiar with the matter. In addition, Roche Holding AG (RHHBY, RO.EB, ROG.VX), which has an interest in gene sequencing, reportedly has been mulling a bid for Life.

Life Technologies declined to comment for this story, as did Thermo Fisher and Roche.

Life was formed nearly five years ago after the merger of its predecessor, Invitrogen Corp., with Applied Biosystems Inc., in a deal valued at $6.7 billion. The company now has about 10,000 employees, sells more than 50,000 products, and owns or licenses more than 5,000 patents. For much of its lifespan, Life has provided equipment used in forensics, to help develop drugs, and to improve food and water safety.

By the end of last year, the company's sales had risen five-fold to $3.8 billion since 2003, but the stock's compound annual growth rate during that time was only 3.83%.

"There's always been the thought that current management is creating an overhang on shares," said David Ferreiro, an Oppenheimer & Co. analyst. "The entire Street thinks that someone else can run Life better than Life can."

At the center of the criticism is Gregory Lucier, Life's chief executive since 2003. Mr. Lucier, has been blamed for spending too freely on acquisitions and not focusing enough resources on increasing sales of the company's consumable research products and services, which comprise roughly 85% of its revenue, according to analysts. Mr. Lucier scored "well below average" and was ranked last in a recent survey by Brendan Wood International that gauged shareholder confidence in the chief executives of 30 large health-care companies.

Despite the company's success in its core business, Life has pushed hard into making next-generation genetic-sequencing machines. Just a few years ago, the cost of sequencing a human genome--the entirety of a person's genetic makeup--was $300,000 and used primarily by academic and commercial researchers.

Costs have come down considerably in recent years, and companies are racing to make faster and more accurate sequencers to help treat patients. As a result, the global market for next-generation sequencing machines, projected to be $1.3 billion this year, is seen rising 61% by 2016, according to Mr. Ferreiro.

To tap into this potential market, Life spent roughly $725 million to buy Ion Torrent Systems Inc., a small but high-potential sequencing company, in 2010. The acquisition gave Life a competitive next-generation sequencing product, though it is still unprofitable and considered inferior to that of market leader Illumina Inc. (ILMN).

Researchers have praised the Ion machines' significantly lower cost and speed, but Life has been criticized for missing deadlines in releasing upgrades to improve what researchers say is its subpar accuracy and ease-of-use. Last year, the company said it would map the human genome for $1,000--a third of what Illumina charges--by the end of 2012, but still hasn't done so.

"They've overpromised and underdelivered," said Kevin Shianna, senior vice president of sequencing operations at the New York Genome Center, a nonprofit research center. "It's still early, but they've hit a bunch of roadblocks."

Some physicians and researchers, however, said that the machines' use of semiconductor chips could allow it to swiftly improve and that their lower costs are attractive to smaller research centers for which Illumina's machines may be unaffordable.

Life has its supporters on Wall Street, including the hedge funds Paulson & Co. and Glenview Capital Management LLC, which are among the company's top three shareholders. The Brendan Wood shareholder confidence survey found that though management scored poorly, Life received relatively high marks in the "confidence in long-term growth" category.

In January, the company's board said it had hired Deutsche Bank and Moelis & Co. to help review its strategic options. The review had begun last summer, when Life's "stock was trading in the low $40s," Mr. Lucier said during a conference call with analysts in February.

If there is a deal, and depending on what the final sale price is, a private-equity buyer could look to cut costs in research and development and manufacturing, and even sell Life's next-generation sequencing business, which could go for between $1.5 billion and $2.4 billion, Mr. Groberg speculated.

Thermo Fisher, a lab instruments and equipment maker with sales of $12.5 billion last year, could possibly get even more value out of the deal, as its overlap with Life's customer base would allow for significant savings in sales and administrative overhead costs. The next-generation sequencing business likely would be considered a bonus to Life's larger consumable business, analysts said.

-Ryan Dezember and Dana Cimilluca contributed to this article.

Write to Joseph Walker at Joseph.Walker@dowjones.com

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