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Idenix: 89% of Patients in Hep C Trial Arm Achieved Viral Suppression

By Ben Fox Rubin Biopharmaceutical firm Idenix Pharmaceuticals Inc. (IDIX) has provided some results from an ongoing Phase 2b study of its lead hepatitis C drug, IDX184, showing positive suppression of the virus. Shares jumped 15% after hours Tuesday to $10.79, as the company's stock often moves sharply following reports related to its or its competitors' hepatitis C drugs. As of the market close, the shares were up 26% so far this year. Idenix is among a handful of companies scrabbling to develop a marketable all-oral Hepatitis C drug, with demand for the treatment expected to be worth billions of dollars a year. Gilead Sciences Inc. (GILD) is a main competitor of Idenix in the race develop such a drug; it spent $11 billion to buy Pharmasset this year, in part to obtain its lead hepatitis C drug candidate, GS-7977. In the Idenix study, Idenix used a mix of its IDX184 with older medications interferon and ribavirin. In all, 31 patients were enrolled and 18 reached extended rapid virologic response, which is when the virus becomes undetectable at four weeks of treatment and again at 12 weeks of treatment. Of those 18 patients, nine were given additional treatments for 12 more weeks. All but one of them achieved sustained virologic response, or undetectable traces of the virus, a month after treatment ended. The other nine patients and those who didn't reach extended rapid virologic response are continuing a regimen of 36 weeks of treatment. Write to Ben Fox Rubin at ben.rubin@dowjones.com

Stock News for Gilead Sciences (GILD)
DateTimeHeadline
08/15/201411:00:37Gilead Notches Victory in Hepatitis C Drug Race
08/15/201409:53:14U.S. Hot Stocks: Hot Stocks to Watch
07/24/201409:21:25MARKET SNAPSHOT: U.S. Stocks: Futures Up; Jobless Claims Tumble
07/24/201407:17:12MARKET SNAPSHOT: U.S. Stocks: Futures Up As Ford, Facebook Rise...
07/24/201406:16:16MARKET SNAPSHOT: U.S. Stocks: Futures Up With Eyes On Ford, Facebook
06/10/201416:34:12Achillion Shares Surge As FDA Lifts Hold On Hepatitis C Drug--2nd...
06/10/201413:47:00Achillion Shares Surge As FDA Clinical Hold On Hep C Treatment...
06/09/201411:24:46Merck to Buy Idenix for $3.85 Billion -- 5th Update
05/21/201422:53:22Despite Data Thefts, the Password Endures
05/15/201418:00:08Third Point Adds New Stakes in American Airlines, Anheuser-Busch
05/07/201419:00:23Gilead Unveils $5 Billion Stock Buyback Plan
04/24/201417:48:51New Hepatitis Drugs Vex Prisons
04/23/201417:02:14MARKET SNAPSHOT: U.S. Stocks Tumble; S&P 500 Ends 6-day Run
04/23/201415:47:47MARKET SNAPSHOT: U.S. Stocks Drift Lower
04/23/201410:40:12MARKET SNAPSHOT: U.S. Stocks Fall; PMI, Home Sales Disappoint
04/23/201410:15:39MARKET SNAPSHOT: U.S. Stocks Fall; PMI Slips In April
04/23/201408:45:47U.S. Stock Futures Hover Near Record
04/22/201417:30:11Gilead Sciences' Results Boosted by Hepatitis C Drug--2nd Update
04/20/201406:17:33MARKET SNAPSHOT: Long View On Stocks Is Best During Weak Earnings...
04/15/201413:30:03Sales of Johnson s New Hepatitis Drug Soars

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