By Michael Calia 
 

Celgene Corp. said its second-quarter profit jumped 25% as sales of its key drug again drove an increase in revenue.

The company's results topped analysts' expectations

Celgene also boosted its adjusted per-share earnings outlook for the year to a range of $3.60 to $3.65, compared with its earlier guidance of $3.50 to $3.60 a share.

"Strong second-quarter operating and financial results demonstrate the significant momentum of our portfolio and support raising our 2014 guidance," Chairman and Chief Executive Bob Hugin said.

The company's results of late have depended on the strength of its leading product, Revlimid, a blood-cancer treatment. That trend continued in the most-recent quarter, with sales of the drug rising 15% to $1.21 billion.

Celgene ran into a bump in the road earlier this month when it said that a late-stage trial of its Otezla drug to treat patients with a form of long-term arthritis failed to meet its primary endpoint. An independent committee recommended that the company continue with the trial. However, the drug received Food and Drug Administration approval earlier this year for another arthritis treatment.

Celgene posted a profit of $597.8 million, or 72 cents a share, up from $478.1 million, or 56 cents a share, in the prior-year quarter. Excluding items such as share-based compensation expenses and costs related to acquired assets, adjusted earnings rose to 90 cents a share from 76 cents a share.

Revenue rose 17% to $1.87 billion.

Analysts had projected earnings of 76 cents a share and revenue of $1.85 billion, according to Thomson Reuters.

Costs and expenses rose 7.6% to $1.11 billion.

Write to Michael Calia at michael.calia@wsj.com

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