(This story has been posted on The Wall Street Journal Online's Health Blog at http://blogs.wsj.com/health.) By Mark Long Here's what's making health news this morning: Health Case Ripples Outward (WSJ): After three days of arguments over the constitutionality of the health-care overhaul, it's impossible to predict how the Supreme Court will rule, but skepticism from some justices heightens the possibility it could be overturned in June. Also: Three Days of Hearings Yield Five Take-Aways. Obesity-Linked Cancers Increase (WSJ): Overall cancer diagnoses in the U.S. have dropped, but several cancers linked to obesity and a sedentary lifestyle have risen each year from 1999 through 2008. Cancer: 'Book of Knowledge' Published (BBC): A large "encyclopedia" detailing how hundreds of different cancer cell lines interact with drugs that could speed development of new treatments was published in Nature. In Cancer Science, Many "Discoveries" Don't Hold Up (Reuters): Forty-seven of 53 "landmark" cancer studies from reputable labs couldn't be replicated, the former head of cancer research for Amgen said in a commentary piece in Nature, dimming the prospects for new drug development. FDA Asks Chelsea Therapeutics for More Data on Northera (Dow Jones Newswires): The FDA declined to approve Northera, a low-blood-pressure drug from Chelsea Therapeutics, saying additional data showing efficacy was required. Image source: iStockphoto -For continuously updated news from The Wall Street Journal, see WSJ.com at http://wsj.com.