FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Gaffin David Joseph

2. Date of Event Requiring Statement (MM/DD/YYYY)
5/26/2016 

3. Issuer Name and Ticker or Trading Symbol

Alkermes plc. [ALKS]

(Last)        (First)        (Middle)

852 WINTER STREET

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
SVP, CLO, Alkermes, Inc. /

(Street)

WALTHAM, MA 02451       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Ordinary Shares   19590   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy)     (1) 12/12/2016   Ordinary Shares   5000   $14.38   D    
Employee Stock Option (Right to Buy)     (1) 6/1/2017   Ordinary Shares   4500   $15.95   D    
Employee Stock Option (Right to Buy)     (1) 11/5/2017   Ordinary Shares   500   $14.13   D    
Employee Stock Option (Right to Buy)     (1) 5/27/2018   Ordinary Shares   1100   $12.29   D    
Employee Stock Option (Right to Buy)     (1) 5/26/2019   Ordinary Shares   7000   $8.55   D    
Employee Stock Option (Right to Buy)     (1) 5/17/2020   Ordinary Shares   3000   $11.74   D    
Employee Stock Option (Right to Buy)     (1) 5/20/2021   Ordinary Shares   2250   $18.105   D    
Employee Stock Option (Right to Buy)     (1) 5/21/2022   Ordinary Shares   41000   $16.55   D    
Employee Stock Option (Right to Buy)   5/28/2014   (2) 5/28/2023   Ordinary Shares   30000   $33.72   D    
Restricted Stock Unit Award   5/28/2014   (3)   (3) Ordinary Shares   2500   $0   D    
Employee Stock Option (Right to Buy)   3/3/2015   (4) 3/3/2024   Ordinary Shares   25000   $47.16   D    
Restricted Stock Unit Award   3/3/2015   (5)   (5) Ordinary Shares   2500   $0   D    
Employee Stock Option (Right to Buy)   2/26/2016   (6) 2/26/2025   Ordinary Shares   17750   $71.23   D    
Restricted Stock Unit Award   2/26/2016   (7)   (7) Ordinary Shares   3300   $0   D    
Performance Restricted Stock Units     (8)   (8) Ordinary Shares   1600     (9) D    
Employee Stock Option (Right to Buy)   3/1/2017   (10) 2/28/2026   Ordinary Shares   36000   $32.27   D    
Restricted Stock Unit Award   3/1/2017   (11)   (11) Ordinary Shares   9000   $0   D    

Explanation of Responses:
( 1)  These options are fully vested in accordance with their terms.
( 2)  Shares subject to the stock option award vest in four equal annual installments commencing on 5/28/14.
( 3)  Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 5/28/14.
( 4)  Shares subject to the stock option award vest in four equal annual installments commencing on 3/3/15.
( 5)  Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 3/3/2015.
( 6)  Shares subject to the stock option award vest in four equal annual installments commencing on 2/26/2016.
( 7)  Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 2/26/2016.
( 8)  Represents the earned but unvested portion of the performance restricted stock units granted to the reporting person on March 3, 2014. The remaining fifty percent of the earned performance restricted stock units will vest on October 5, 2016.
( 9)  Each performance restricted stock unit represents a contingent right to receive one ordinary share of Alkermes plc.
( 10)  Shares subject to the stock option award vest in four equal annual installments commencing on 3/1/2017.
( 11)  Shares subject to the restricted stock unit award vest in equal annual installments over a four year period, commencing on 3/1/2017.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Gaffin David Joseph
852 WINTER STREET
WALTHAM, MA 02451

SVP, CLO, Alkermes, Inc.

Signatures
/s/ Jennifer Baptiste, attorney-in-fact for David J Gaffin 6/1/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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