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Protalix Gets $25 Million Milestone Payment For Rare-Disease Drug

By Kristin Jones Protalix BioTherapeutics Inc. (PLX) has received a $25 million milestone payment from Pfizer Inc. (PFE) after the U.S. Food and Drug Administration approved its new drug for the treatment of Gaucher disease. On May 1, U.S. regulators approved taliglucerase alfa, sold as Elelyso, for the treatment of type 1 Gaucher disease, a genetic disorder that can cause enlargement of the spleen and liver, as well as lung disease and bone problems. Pfizer and Protaliz entered an exclusive agreement for the development and commercialization of Elelyso in November 2009. Under the terms of the deal, Pfizer has an exclusive license to sell Elelyso, except in Israel. Elelyso, an infusion administered by health-care professionals every other week, is the first plant-derived cell-based enzyme replacement. It will compete in the U.S. with the Gaucher-disease treatment Cerezyme, produced by Genzyme, the U.S. biotechnology unit of Sanofi S.A. (SNY, SAN.FR) and Shire PLC's (SHPGY, SHP.LN) Vpriv. Protalix shares rose 2.4% to $6.85 in premarket trading. The stock is up 36% so far this year. Write to Kristin Jones at

Stock News for Protalix Biotherapeutics (PLX)
03/12/201516:52:07Annual Report (10-k)
03/12/201516:32:12Current Report Filing (8-k)
02/13/201515:54:14Amended Statement of Ownership (sc 13g/a)
02/12/201507:38:44Current Report Filing (8-k)
02/11/201514:13:50Amended Statement of Ownership (sc 13g/a)
02/02/201507:07:51Current Report Filing (8-k)
01/08/201507:10:55Current Report Filing (8-k)
01/05/201507:07:02Current Report Filing (8-k)
11/17/201416:31:18Initial Statement of Beneficial Ownership (3)
11/12/201407:32:36Current Report Filing (8-k)
11/10/201416:34:00Quarterly Report (10-q)
11/03/201417:06:55Statement of Changes in Beneficial Ownership (4)
11/03/201417:05:13Initial Statement of Beneficial Ownership (3)
10/29/201414:33:41Additional Proxy Soliciting Materials (definitive) (defa14a)
10/09/201416:30:08Proxy Statement (definitive) (def 14a)
10/06/201418:00:25Statement of Changes in Beneficial Ownership (4)
09/29/201417:00:56Proxy Statement - Notice of Shareholders Meeting (preliminary...
09/29/201416:31:14Current Report Filing (8-k)
09/18/201417:59:39Statement of Changes in Beneficial Ownership (4)
09/18/201417:58:30Statement of Changes in Beneficial Ownership (4)

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