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Protalix Gets $25 Million Milestone Payment For Rare-Disease Drug

By Kristin Jones Protalix BioTherapeutics Inc. (PLX) has received a $25 million milestone payment from Pfizer Inc. (PFE) after the U.S. Food and Drug Administration approved its new drug for the treatment of Gaucher disease. On May 1, U.S. regulators approved taliglucerase alfa, sold as Elelyso, for the treatment of type 1 Gaucher disease, a genetic disorder that can cause enlargement of the spleen and liver, as well as lung disease and bone problems. Pfizer and Protaliz entered an exclusive agreement for the development and commercialization of Elelyso in November 2009. Under the terms of the deal, Pfizer has an exclusive license to sell Elelyso, except in Israel. Elelyso, an infusion administered by health-care professionals every other week, is the first plant-derived cell-based enzyme replacement. It will compete in the U.S. with the Gaucher-disease treatment Cerezyme, produced by Genzyme, the U.S. biotechnology unit of Sanofi S.A. (SNY, SAN.FR) and Shire PLC's (SHPGY, SHP.LN) Vpriv. Protalix shares rose 2.4% to $6.85 in premarket trading. The stock is up 36% so far this year. Write to Kristin Jones at

Stock News for Protalix Biotherapeutics (PLX)
09/16/201617:02:40Statement of Changes in Beneficial Ownership (4)
08/10/201607:40:25Current Report Filing (8-k)
08/08/201616:54:43Quarterly Report (10-q)
08/08/201616:41:42Current Report Filing (8-k)
07/07/201607:37:38Current Report Filing (8-k)
07/01/201617:06:03Proxy Statement (definitive) (def 14a)
06/16/201616:58:44Proxy Statement - Notice of Shareholders Meeting (preliminary...
06/07/201609:35:44Current Report Filing (8-k)
06/06/201607:09:10Current Report Filing (8-k)
05/09/201617:25:40Quarterly Report (10-q)
05/09/201607:17:46Current Report Filing (8-k)
04/22/201617:02:58Amended Annual Report (10-k/a)
04/08/201617:01:54Current Report Filing (8-k)
04/07/201609:13:22Amended Statement of Ownership (sc 13g/a)
04/01/201617:02:05Current Report Filing (8-k)
03/09/201619:46:35Protalix BioTherapeutics Presents Positive Six and Twelve Month...
03/08/201607:38:57Current Report Filing (8-k)
03/03/201607:07:28Current Report Filing (8-k)
02/12/201613:07:16Amended Statement of Ownership (sc 13g/a)
02/11/201614:52:39Amended Statement of Ownership (sc 13g/a)

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