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Protalix Gets $25 Million Milestone Payment For Rare-Disease Drug

By Kristin Jones Protalix BioTherapeutics Inc. (PLX) has received a $25 million milestone payment from Pfizer Inc. (PFE) after the U.S. Food and Drug Administration approved its new drug for the treatment of Gaucher disease. On May 1, U.S. regulators approved taliglucerase alfa, sold as Elelyso, for the treatment of type 1 Gaucher disease, a genetic disorder that can cause enlargement of the spleen and liver, as well as lung disease and bone problems. Pfizer and Protaliz entered an exclusive agreement for the development and commercialization of Elelyso in November 2009. Under the terms of the deal, Pfizer has an exclusive license to sell Elelyso, except in Israel. Elelyso, an infusion administered by health-care professionals every other week, is the first plant-derived cell-based enzyme replacement. It will compete in the U.S. with the Gaucher-disease treatment Cerezyme, produced by Genzyme, the U.S. biotechnology unit of Sanofi S.A. (SNY, SAN.FR) and Shire PLC's (SHPGY, SHP.LN) Vpriv. Protalix shares rose 2.4% to $6.85 in premarket trading. The stock is up 36% so far this year. Write to Kristin Jones at

Stock News for Protalix Biotherapeutics (PLX)
10/05/201508:00:00Protalix BioTherapeutics to Explore Non Alcoholic Steato Hepatitis...
10/01/201516:32:24Proxy Statement (definitive) (def 14a)
09/21/201520:46:07Protalix BioTherapeutics Reports Positive Phase I/II Interim...
09/09/201507:07:44Current Report Filing (8-k)
08/10/201518:07:55Quarterly Report (10-q)
08/10/201516:39:28Current Report Filing (8-k)
07/28/201503:45:00CollPlant Names Shomrat Shurtz Senior Director of Business Development
06/09/201512:06:18Statement of Ownership (sc 13g)
05/14/201507:30:00Protalix BioTherapeutics to Present at Two Upcoming Healthcare...
05/07/201517:27:58Statement of Changes in Beneficial Ownership (4)
05/07/201517:27:31Statement of Changes in Beneficial Ownership (4)
05/07/201517:25:21Statement of Changes in Beneficial Ownership (4)
05/07/201517:24:28Statement of Changes in Beneficial Ownership (4)
05/07/201517:12:22Securities Registration: Employee Benefit Plan (s-8)
05/07/201517:10:14Quarterly Report (10-q)
05/07/201516:30:00Protalix BioTherapeutics Reports First Quarter 2015 Financial...
04/21/201506:08:51Statement of Ownership (sc 13g)
04/20/201516:40:10Statement of Ownership (sc 13g)
03/12/201516:52:07Annual Report (10-k)
03/12/201516:32:12Current Report Filing (8-k)

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