ADVFN - Advanced Financial Network.
HOME» AMEX » P » PLX Stock Price » PLX Stock News

Protalix Biotherapeutics Share News

 Protalix Biotherapeutics, Stock Price
PLX Stock Price
 Protalix Biotherapeutics, Stock Chart
PLX Stock Chart
 Protalix Biotherapeutics, Stock News
PLX Stock News
 Protalix Biotherapeutics, Company Information
PLX Company Information
 Protalix Biotherapeutics, Stock Trades
PLX Stock Trades

Genzyme To End Fabrazyme Rationing By Mid-2011

By Thomas Gryta Of DOW JONES NEWSWIRES NEW YORK -(Dow Jones)- Genzyme Corp. (GENZ) expects to stop rationing its rare disease treatment Fabrazyme by mid-2011, almost two years after the shortage began. The problem stemmed from the temporary shutdown of Genzyme's Allston, Mass., plant due to a viral contamination last year. The facility is the sole source of Gaucher's disease treatment Cerezyme and Fabry disease drug Fabrazyme, and shortages of the drugs have significantly hurt Genzyme's business. Adding to that, the efficiency of Fabrazyme production has been slower than expected since restarting the Allston plant. Patients affected by both diseases lack specific enzymes--which the drugs replace--that break down certain types of fats, causing them to build up in the body and leading to major problems including pain, skeletal complications, organ failure and death. For both drugs, a normal dose generally means getting the drug twice a month. Fabrazyme patients in the U.S. have received a dose every other month for the past few months, although that is increasing to a monthly dose this month. The company previously said that current Fabrazyme allocations would remain in place for the third quarter and shipments would increase in the fourth quarter, but it provided no guidance for resumption of normal doses. Genzyme has said that U.S. Cerezyme patients will be returning to normal doses this month with all patients around the world returning to normal in the fourth quarter. The news comes as Genzyme has been under siege from activist investors in recent months. The company recently rejected an $18.5 billion unsolicited takeover offer from France's Sanofi-Aventis SA (SNY, SAN.FR). The Allston plant has been plagued by problems, including numerous failed regulatory inspections and the temporary shutdown, all of which has significantly hurt Genzyme's earnings. The company recently extended the timeline for fixing the issues by a year, meaning regulatory oversight of the plant could last as many as nine years. The problems have allowed the entrance of competitors for Cerezyme and Fabrazyme. Shire PLC (SHPGY, SHP.LN) makes Gaucher's treatment Vpriv, which is approved in the U.S. and Europe. It already sells Fabry disease drug Replagal in Europe and plans to file for U.S. approval. Protalix BioTherapeutics Inc. (PLX) is developing a Gaucher's disease treatment with Pfizer Inc. (PFE) that is under Food and Drug Administration review. Because of the shortages, the FDA allowed all the drugs to be used under a special protocol last year, despite not yet being approved for marketing. -By Thomas Gryta, Dow Jones Newswires; 212-416-2169; thomas.gryta@dowjones.com

Stock News for Protalix Biotherapeutics (PLX)
DateTimeHeadline
06/19/201309:17:54U.S. HOT STOCK FUTURES: HOT STOCKS TO WATCH
06/19/201308:26:20Protalix Reaches Pact to Transfer Technology for Gaucher Disease...
04/29/201308:40:57Protalix BioTherapeutics Treatment for Gaucher Disease Approved...
12/06/201208:36:34Protalix Signs Deal With Pfizer to Continue Managing Elelyso...
06/22/201209:50:54EMA Recommends Against Marketing Authorization to Pfizer and...
06/11/201208:29:40Protalix Gets $25 Million Milestone Payment For Rare-Disease...
05/02/201216:17:45US Stocks Trade Lower Late On Concerns Over Hiring, Europe
05/02/201214:40:14US Stocks Edge Lower On Weak Private-Sector Hiring
05/01/201217:37:05CORRECT: FDA Approves Protalix, Pfizer Drug To Treat Gaucher...
05/01/201217:07:24FDA Approves Protalix, Pfizer Drug To Treat Gaucher Disease
08/17/201108:57:24FDA Accepts Protalix Resubmission For Gaucher Disease Drug; Shares...
02/25/201107:31:34Protalix: FDA Requests More Information On Gaucher's Drug
10/01/201011:53:15Genzyme Efforts To End Cerezyme Shortage Proceeding
09/15/201013:31:11Genzyme To End Fabrazyme Rationing By Mid-2011
07/12/201007:02:50FDA May Not Rule On Protalix's Gaucher's Treatment Until 2011
02/19/201007:52:16Shire 4Q Profit Up 23% As Drug Sales Offset Generic Losses
12/01/200912:10:05Pfizer-Protalix Deal Strengthens Competition For Genzyme
12/01/200907:25:14Pfizer To Pay Protalix Up To $115 Million In Gaucher's Deal

Protalix Biotherapeutics and other American Stock Exchange stock quotes are delayed by at least 20 minutes.
All other stock price data is delayed by at least 15 minutes unless otherwise stated. By accessing the services available at ADVFN you are agreeing to be bound by ADVFN's Terms & Conditions
Contact Us | Copyright 1999-2007 ADVFN PLC. | Privacy Policy | Investment Warning | Data accreditations | Investor Relations

ADVFNADVFN ItalyADVFN GermanyADVFN FranceADVFN BrazilADVFN JapanADVFN UKADVFN US noad